The 17th-ranked St. John's Red Storm look to extend their winning streak to 13 games when they battle the Creighton Bluejays in a key Big East Conference matchup on Saturday. Creighton is coming off a 91-84 win over fifth-ranked UConn on Wednesday, while St. John's topped Marquette 76-70 that same night. The Bluejays (14-13, 8-8 Big East), who are tied for fourth in the conference, are 3-7 on the road this season. The Red Storm (21-5, 14-1 Big East), who lead the league by one-half game over UConn, are 12-2 on their home court.

Tipoff from Madison Square Garden in New York is set for noon ET. St. John's is a 12.5-point favorite in the latest St. John's vs. Creighton odds from DraftKings Sportsbook, while the over/under for total points scored is 154.5. Before making any Creighton vs. St. John's picks, check out the men's college basketball predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every college basketball game 10,000 times and it entered Week 16 on a sizzling 11-1 run on its top-rated over/under college basketball picks dating back to last season, and is on a 13-7 run on top-rated CBB side picks. Anyone following its college basketball betting advice at sportsbooks and on betting apps could have seen strong returns.

Now, the model has simulated Creighton vs. St. John's 10,000 times and just revealed its coveted men's college basketball picks and betting predictions. You can head to SportsLine now to see the model's picks. Here are several men's college basketball odds and men's college basketball betting lines for St. John's vs. Creighton:

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Top Creighton vs. St. John's predictions

SportsLine's model is going Under on the total (154.5 points). The total has risen one point since the opening line, creating value on this side. These teams have slightly trended to the Under this year with 54% of St. John's games hitting that side of the total, while 52% of Creighton's games have failed to reach the total.

This time around the model is projecting 153 combined points as the Under hits 50.2% of the time. 

How to make St. John's vs. Creighton picks

The model also says one side of the spread hits more than 60% of the time. You can only see that pick at SportsLine.

So who wins St. John's vs. Creighton, and which side of the spread hits more than 60% of the time? Visit SportsLine now to see which side of the Creighton vs. St. John's spread to back, all from the advanced model that has simulated this game 10,000 times, and find out.